![]() ![]() Results: StOHV is more effective than spOHV in eliciting Hyperventilation Induced High Amplitude Rhythmic Slow activity (HIHARS) on EEG or normal adults, significantly reducing pETCO2 power density of slow EEG frequencies and vCBF. Digital video EEG, EOG, EMG, Respiration Rate, Heart Rate,pO2, end tidal pCO2 and Cerebral Blood Flow are monitored before, during and after OHV performed in sitting (st) and supine (sp) position. Cohort of 22 healthy adults subjects, 14 females, 8 males, mean age 29.5 years recruited. Method: Respiratory rate 30/min, producing three fold elevation in total expiratory vol/min (VE), duration 4 minutes. Objective: A Standardised Optimal Hyperventilation Protocol (SOHVP), which elicited Hyperventilation Induced High Amplitude Rhythmic Slow activity (HIHARS) during EEG controlling for posture seated (stOHV) and supine (spOHV) is presented and validated. Effects of posture are poor studied quantitatively. ![]() Four criteria determine the magnitude of HV response: vigorous exchange of air, blood glucose levels, age of subject, and posture. The mechanism of action by which Hyperventilation (HV) produces slow theta/delta waves on EEG remains conjectural. It induces hypocapnia, which elicits changes in brain wave activity that may be diagnostically useful. Hyperventilation is used as an activation procedure during EEG. ![]()
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